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Publications

A synthetic, three-dimensional bone marrow hydrogel

Biomaterials 2022

A synthetic, three-dimensional bone marrow hydrogel

Genetic Mutations Associated with Hormone-Positive Breast Cancer in a Small Cohort of Ethiopian Women

Annals of Biomedical Engineering 2021

Genetic Mutations Associated with Hormone-Positive Breast Cancer in a Small Cohort of Ethiopian Women

Localized characterization of brain tissue mechanical properties by needle induced cavitation rheology and volume controlled cavity expansion

Journal of the Mechanical Behavior of Biomedical Materials 2021

Localized characterization of brain tissue mechanical properties by needle induced cavitation rheology and volume controlled cavity expansion

OrgDyn: feature- and model-based characterization of spatial and temporal organoid dynamics

Bioinformatics 2020

OrgDyn: feature- and model-based characterization of spatial and temporal organoid dynamics

The 2020 Young Innovators of Cellular and Molecular Bioengineering

Cellular and Molecular Bioengineering 2020

The 2020 Young Innovators of Cellular and Molecular Bioengineering

Seeded laser-induced cavitation for studying high-strain-rate irreversible deformation of soft materials

Soft Matter 2020

Seeded laser-induced cavitation for studying high-strain-rate irreversible deformation of soft materials

Cavitation in soft matter

PNAS 2020

Cavitation in soft matter

Vascularized biomaterials to study cancer metastasis

Advanced Healthcare Materials 2020

Vascularized biomaterials to study cancer metastasis

Tumor cell-organized fibronectin is required to maintain a dormant breast cancer population

Science Advances 2020

Tumor cell-organized fibronectin is required to maintain a dormant breast cancer population

Control of Astrocyte Quiescence and Activation in a Synthetic Brain Hydrogel

Advanced Healthcare Materials 2020

Control of Astrocyte Quiescence and Activation in a Synthetic Brain Hydrogel

Differentiation of Pathogenic Th17 Cells is Negatively Regulated by Let-7 MicroRNAs in a Mouse Model of Multiple Sclerosis

Frontiers in Immunology 2020

Differentiation of Pathogenic Th17 Cells is Negatively Regulated by Let-7 MicroRNAs in a Mouse Model of Multiple Sclerosis

Emerging concepts and tools in cell mechanomemory

Annals of Biomedical Engineering 2020

Emerging concepts and tools in cell mechanomemory

2D or 3D? How in vitro cell motility is conserved across dimensions, and predicts in vivo invasion

Bioengineering & Translational Medicine 2019

2D or 3D? How in vitro cell motility is conserved across dimensions, and predicts in vivo invasion

Applicability of drug response metrics for cancer studies using biomaterials

Philosophical Transactions of the Royal Society B 2019

Applicability of drug response metrics for cancer studies using biomaterials

An omentum-inspired 3D PEG hydrogel for identifying ECM drivers of drug resistant ovarian cancer

APL Bioengineering 2019

An omentum-inspired 3D PEG hydrogel for identifying ECM drivers of drug resistant ovarian cancer

Biomechanical microenvironment regulates fusogenicity of breast cancer cells

ACS Biomaterials and Bioengineering 2019

Biomechanical microenvironment regulates fusogenicity of breast cancer cells

Implantable pre-metastatic niches for the study of microenvironmental regulation of disseminated human tumour cells

Nature Biomedical Engineering 2018

Implantable pre-metastatic niches for the study of microenvironmental regulation of disseminated human tumour cells

Cross-platform mechanical characterization of lung tissue

PLoS One 2018

Cross-platform mechanical characterization of lung tissue

Tumor‐stroma interactions differentially alter drug sensitivity based on the origin of stromal cells

Molecular Systems Biology 2018

Tumor‐stroma interactions differentially alter drug sensitivity based on the origin of stromal cells

Zwitterionic PEG-PC hydrogels modulate the foreign body response in a modulus-dependent manner

Biomacromolecules 2018

Zwitterionic PEG-PC hydrogels modulate the foreign body response in a modulus-dependent manner

Anomalous diffusion as a descriptive model of cell migration

APL Bioengineering 2018

Anomalous diffusion as a descriptive model of cell migration

Mechanosensing of Integrin 6 and EGFR Converges at Calpain 2

Biomaterials 2018

Mechanosensing of Integrin 6 and EGFR Converges at Calpain 2

Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+–NFAT signaling

Genes and Development 2018

Acetyl-CoA promotes glioblastoma cell adhesion and migration through Ca2+–NFAT signaling

Control of Thiol-Maleimide Reaction Kinetics in PEG Hydrogel Networks

Acta Biomaterialia 2018

Control of Thiol-Maleimide Reaction Kinetics in PEG Hydrogel Networks

Complementary, semiautomated methods for creating multidimensional PEG-based biomaterials

ACS Biomaterials Science and Engineering 2018

Complementary, semiautomated methods for creating multidimensional PEG-based biomaterials

Comparative Study of Multicellular Tumor Spheroid Formation Methods and Implications for Drug Screening

ACS Biomaterials Science and Engineering 2018

Comparative Study of Multicellular Tumor Spheroid Formation Methods and Implications for Drug Screening

Strain-stiffening gels based on latent crosslinking

Soft Matter 2017

Strain-stiffening gels based on latent crosslinking

A Biomaterial Screening Approach to Reveal Microenvironmental Mechanisms of Drug Resistance

Integrative Biology 2017

A Biomaterial Screening Approach to Reveal Microenvironmental Mechanisms of Drug Resistance

A Student-Created, Open Access, Living Textbook

Chemical Engineering Education 2017

A Student-Created, Open Access, Living Textbook

Differential cathepsin responses to inhibitor-induced feedback: E-64 and cystatin C elevate active cathepsin S and suppress active cathepsin L in breast cancer cells

The International Journal of Biochemistry & Cell Biology 2016

Differential cathepsin responses to inhibitor-induced feedback: E-64 and cystatin C elevate active cathepsin S and suppress active cathepsin L in breast cancer cells

Biochemical and biomechanical drivers of cancer cell metastasis, drug response and nanomedicine

Drug Discovery Today 2016

Biochemical and biomechanical drivers of cancer cell metastasis, drug response and nanomedicine

The predictive link between matrix and metastasis

Current Opinion in Chemical Engineering 2016

The predictive link between matrix and metastasis

Mechanics of intact bone marrow

Journal of the Mechanical Behavior of Biomedical Materials

Mechanics of intact bone marrow

Fewer bacteria adhere to softer hydrogels

ACS Applied Materials and Interfaces 2015

Fewer bacteria adhere to softer hydrogels

Smooth muscle stiffness sensitivity is driven by soluble and insoluble ECM chemistry

Cellular and Molecular Bioengineering 2015

Smooth muscle stiffness sensitivity is driven by soluble and insoluble ECM chemistry

Thermal-responsive behavior of a cell compatible chitosan:pectin hydrogel

Biomacromolecules 2015

Thermal-responsive behavior of a cell compatible chitosan:pectin hydrogel

A cell-ECM screening method to predict breast cancer metastasis

Integrative Biology 2015

A cell-ECM screening method to predict breast cancer metastasis

Sorafenib resistance and JNK signaling in carcinoma during extracellular matrix stiffening

Biomaterials 2014

Sorafenib resistance and JNK signaling in carcinoma during extracellular matrix stiffening

Promoting cell adhesion on slippery phosphorylcholine hydrogel surfaces

J Materials Chemistry B 2014

Promoting cell adhesion on slippery phosphorylcholine hydrogel surfaces

A heparin decamer bridges a growth factor and an oligolysine by different charge-driven interactions

Biomacromolecules 2013

A heparin decamer bridges a growth factor and an oligolysine by different charge-driven interactions

PEG-Phosphorylcholine hydrogels as tunable and versatile platforms for mechanobiology

Biomacromolecules 2013

PEG-Phosphorylcholine hydrogels as tunable and versatile platforms for mechanobiology

Bio-inspired materials for parsing matrix physicochemical control of cell migration

Integrative Biology 2012

Bio-inspired materials for parsing matrix physicochemical control of cell migration

Marrow-derived stem cell motility in 3D synthetic scaffold is governed by geometry along with adhesivity and stiffness

Biotechnology and Bioengineering 2011

Marrow-derived stem cell motility in 3D synthetic scaffold is governed by geometry along with adhesivity and stiffness

Autocrine-controlled formation and function of tissue-like aggregates by primary hepatocytes in micropatterned hydrogel arrays

Tissue Engineering Part A 2011

Autocrine-controlled formation and function of tissue-like aggregates by primary hepatocytes in micropatterned hydrogel arrays

The influence of ascorbic acid, TGF-1, and cell-mediated remodeling on the bulk mechanical properties of 3-D PEG-fibrinogen constructs

Biomaterials 2009

The influence of ascorbic acid, TGF-1, and cell-mediated remodeling on the bulk mechanical properties of 3-D PEG-fibrinogen constructs

ECM compliance regulates osteogenesis by influencing MAPK signaling downstream of RhoA and ROCK

Journal of Bone and Mineral Research 2009

ECM compliance regulates osteogenesis by influencing MAPK signaling downstream of RhoA and ROCK

The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system

Biomaterials 2008

The effects of matrix stiffness and RhoA on the phenotypic plasticity of smooth muscle cells in a 3-D biosynthetic hydrogel system

The regulation of osteogenesis by ECM rigidity in MC3T3-E1 cells requires MAPK activation

Journal of Cellular Physiology 2007

The regulation of osteogenesis by ECM rigidity in MC3T3-E1 cells requires MAPK activation

The emergence of ECM mechanics and cytoskeletal tension as important regulators of cell function

Cell Biochemistry and Biophysics 2007

The emergence of ECM mechanics and cytoskeletal tension as important regulators of cell function

A novel 3-D model to quantify metastatic melanoma invasion

Molecular Cancer Therapeutics 2007

A novel 3-D model to quantify metastatic melanoma invasion